Symbol
Name
ID

Il2ra
interleukin 2 receptor, alpha chain
MGI:96549

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased lymphocyte proliferation in response to anti-CD3	Decreased circulating IgA level	Increased circulating IgE level	Decreased specific anti-polysaccharide antibody level	Hemolytic anemia	Autoimmune hemolytic anemia	B lymphocytopenia	Decreased proportion of CD4+CD25+ regulatory T cells	Decreased CD4:CD8 ratio	T lymphocytopenia	Hepatosplenomegaly
Disease(s) Associated with IL2RA
immunodeficiency 41

Mouse Phenotypes

enlarged spleen

anemia

hemolytic anemia

decreased erythrocyte cell number

decreased hematocrit

decreased hemoglobin content

decreased mean corpuscular hemoglobin

decreased mean corpuscular hemoglobin concentration

decreased mean corpuscular volume

increased neutrophil cell number

increased memory T cell number

decreased lymphocyte cell number

increased lymphocyte cell number

increased large unstained cell number

abnormal T cell morphology

abnormal spleen morphology

abnormal B cell physiology

increased IgA level

increased IgG1 level

increased IgG2a level

increased IgG2b level

increased IgG level

abnormal T cell physiology

abnormal T cell activation

abnormal regulatory T cell physiology

Availability

Mouse Genotype

Il2ra^M1J/Il2ra^M1J

Il2ra^{tm1b(EUCOMM)Wtsi}/Il2ra^{tm1b(EUCOMM)Wtsi}

Il2ra^tm1Dw/Il2ra^tm1Dw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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